BETA-ADRENERGIC BLOCKADE AND THE METABOLIC RESPONSE TO SURGERY
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چکیده
منابع مشابه
Beta-adrenergic blockade and the metabolic response to surgery.
The effect of the administration of propranolol 0.15 mg per kg body weight i.v. on the metabolic response to pelvic surgery was compared with results in similar patients who had not received propranolol. The only significant difference between the two groups was a lower plasma insulin concentration in the beta-blockade patients after 60 and 90 min of surgery. The glycaemic response to surgery w...
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This overview is concerned with the causes of nonresponsiveness to the hypotensive action of beta-adrenergic blocking drugs. The overall hemodynamic response, i.e., a secondary decrease in peripheral vascular resistance, is unrelated to the primary decrease in cardiac output. The reduction in vascular resistance may be triggered by mechanisms residing in the central nervous system, the arterial...
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Early studies with propranolol and other betablockers, mainly employing intravenous administration, demonstrated elective and prophylactic control of supraventricular and ventricular tachyarrhythmias periand postoperatively. There has been particular focus on esmolol, which is an ultrashort acting beta1 selective antagonist that is rapidly hydrolysed by red cell esterases with a half life of ab...
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Many of the changes in cardiac performance that take place during exercise resemble those that result from stimulation of the sympathetic nervous pathways to the heart. It has therefore been thought likely that an increase in sympathetic nervous activity occurs during exercise and is important in the mediation of the associated cardiac response. To test this hypothesis a variety of experimental...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1980
ISSN: 0007-0912
DOI: 10.1093/bja/52.12.1231